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Overview
Chantix® (its chemical name is varenicline) is a prescription drug designed to aid people who want to quit smoking. Chantix® first approved for sale in the United States during 2006, is also marketed under the brand name Champix® in Europe and other countries. According to information published by its manufacturer, as of June, 2009, Chantix® has been prescribed to over 10 million people worldwide since being launched.

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In January 2008, Pfizer, Inc., the manufacturer of Chantix®, revised the label for Chantix® by adding a safety warning as mandated by the FDA. The new warning advised prescribing physicians to monitor their patients fro neuropsychiatric symptoms associated with the use of Chantix®. These symptoms include suicidal ideation, suicidal behavior, agitation, changes in behavior, and depressed mood. In May 2008, the Chantix® label and patient information was again revised to warn patients that they should stop taking Chantix® and contact their healthcare providers immediately if they experience depressed mood, agitation, thoughts of suicide, suicidal behavior or changes in behavior that are atypical. This warning was elevated to a “Blacked Box” in 2009.

If you or a loved one have developed diabetes or pre-diabetes, or suffered physical self-harm after taking Chantix® and would like us to evaluate the situation, click HERE.

Chantix Information Center

How Chantix® Works In The Body

Chantix® and Diabetes and Smoking and Diabetes

Chantix® and Suicide Ideation

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Article Published in the British Medical Journal

A study published in the October 2009 issue of the British Medical Journal compared the risk of self-harm, suicidal thoughts or depression in people using Chantix® to people using other smoking cessation products – most notably Zyban®. The authors concluded that there was “no clear evidence of an increased risk of self harm, suicidal thoughts or depression in people prescribed varenicline [Chantix®] compared with those prescribed other smoking cessation products.” BMJ 2009; 339:b3805.

However, the study did not compare the risk of such side effects among users of Chantix to the risk among the general population. The authors cite several limitations to their analysis of the data reviewed in their study and caution that “…a twofold increased risk of self harm with varenicline [Chantix®] cannot be ruled out…”

If you or a loved one have developed diabetes or pre-diabetes, or suffered physical self-harm after taking Chantix® and would like us to evaluate the situation, click HERE.

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If you or a loved one have developed diabetes or pre-diabetes, or suffered physical self-harm after taking Chantix® and would like us to evaluate the situation, click HERE.

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